Catalog number: SBB-PS0010, 2 mg
A Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases (Ex=345 nm and Em=445 nm).
Suc-Leu-Leu-Val-Tyr-AMC (LLVY-AMC)
SKU: 0010
$69.00Price
Suc-LLVY-AMC a 7-amino-4-methylcoumarin (AMC) labeled fluorogenic substrate can be used to measure the chymotrypsin–like activity of the 20S and 26S proteasome as well as calpains and other chymotrypsin-like proteases. Working concentrations of this substrate is 20-50 µM. Cleavage of the peptide by the enzymes liberates the fluorophore AMC which generates strong increase in fluorescence fluorescent that can be monitored fluorimetrically at Ex=345 nm and Em=445 nm.