Proteasome
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Catalog number: SBB-KP0037
This kit is designed to test for specific activity of 20S immunoproteasome. The kit provides purified 20S immunoproteasome and is designed to test for Chymotrypsin-like activity (Suc-LLVY-AMC), and Caspase-like activity of the immunoproteasome subunits ß1i/ PSMB9 (PAL-AMC), and ß5i/PSMB8 (ANW-AMC).
Catalog number: SBB-PP0004, 25 μg
Highly active protein complex that has been purified from human peripheral blood mononuclear cell (PBMC) . Immunoproteasome is recognized as a strong drug target for autoimmune disease and cancer. This immunoproteasome is supplied at >95% purity and experiments should be carried out at 20S immunoproteasome concentrations between 2-5 nM.
Catalog Number: SBB-PP0083, 50 μg
Highly active protein complex that has been purified from mouse spleen and is supplied at >95% purity. Immunoproteasome is recognized as a strong drug target for autoimmune disease and cancer. This immunoproteasome is supplied at >95% purity and experiments should be carried out at 20S immunoproteasome concentrations between 2-5 nM.
Catalog Number: SBB-PP0046, 50ug
Highly active protein complex that has been purified from rat spleen and is supplied at >95% purity. Immunoproteasome is recognized as a strong drug target for autoimmune disease and cancer. This immunoproteasome is supplied at >95% purity and experiments should be carried out at 20S immunoproteasome concentrations between 2-5 nM.
Catalog number: SBB-KP0038
This kit is designed to test for specific activity of 20S proteasome. The kit provides purified 20S proteasome and is designed to test for Chymotrypsin-like activity (Suc-LLVY-AMC), Caspase-like activity of the proteasome subunits ß1/PSMB6 (LLE-AMC), and Chymotrypsin-like activity of ß5/PSMB5 (WLA-AMC).
Catalog number: SBB-PP0005, 50 μg
Highly active protein complex that has been purified from human red blood cells (RBC). The Human 20S proteasome is able to proteolytically degrade substrates in an ATP-independent manner. The 20S core can be activated chemically with SDS (0.035%) or by the addition of PA28. Initial experiments should be carried out at 20S proteasome concentrations between 2-5 nM.
Catalog Number: SBB-PP0047, 50 μg
Highly active protein complex that has been purified from mouse red blood cells (RBC). The rat 20S proteasome is able to proteolytically degrade substrates in an ATP-independent manner. The 20S core can be activated chemically with SDS (0.035%) or by the addition of PA28. Initial experiments should be carried out at 20S proteasome concentrations between 2-5 nM.
Catalog Number: SBB-PP0086, 50 μg
Highly active protein complex that has been purified from rat red blood cells (RBC). The rat 20S proteasome is able to proteolytically degrade substrates in an ATP-independent manner. The 20S core can be activated chemically with SDS (0.035%) or by the addition of PA28. Initial experiments should be carried out at 20S proteasome concentrations between 2-5 nM.
Catalog number: SBB-PS0009, 2 mg
Ac-ANW-AMC is a fluorogenic peptidyl substrate for measuring chymotrypsin-like activity of the immunoproteasome. Hydrolysis of this substrate by the β5i subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm.
Catalog number: SBB-PS0007, 2 mg
Ac-PAL-AMC is a fluorogenic peptidyl substrate for measuring caspase-like activity of the immunoproteasome. Hydrolysis of this substrate by the β1i subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm.
Catalog number: SBB-PS0008, 2 mg
Ac-WLA-AMC is a fluorogenic peptidyl substrate for measuring chymotrypsin-like activity of the proteasome. Hydrolysis of this substrate by the β5 subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm.
Catalog number: SBB-PS0010, 2 mg
A Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases (Ex=345 nm and Em=445 nm).
Catalog number: SBB-PS0006, 2 mg
Z-LLE-AMC is a fluorogenic peptidyl substrate for measuring caspase-like activity of the proteasome. Hydrolysis of this substrate by the β1 subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm.